EPN Machine — Electroporation Microneedling Pen for Transdermal Serum Delivery
A dual-action mesotherapy platform combining automatic microneedling with electroporation to deliver serums and growth factors deep into the dermis. Class II medical device, CE + ISO 13485 certified. Wholesale pricing for clinics and distributors.
20× Absorption Boost
0.0–2.0mm Adjustable Depth
9-Pin 33G Cartridges
CE + ISO 13485

Product Overview

The IVIVA EPN Machine is a dual-action electroporation microneedling pen that combines automatic microneedling (Auto-MTS) with electroporation. Microneedling creates controlled micro-channels that stimulate collagen and elastin, while gentle electrical pulses open transient hydrophilic pores in cell membranes — dramatically increasing the absorption of serums, hyaluronic acid, peptides and growth factors.
Unlike a conventional derma pen, the EPN adds electroporation to push active ingredients up to 20× deeper than topical application alone. With an infinitely adjustable 0.0–2.0 mm needle depth, a 9-pin 33G disposable cartridge, and 5-level electroporation intensity control, it treats everything from fine lines and acne scars to hair restoration.
Technical Specifications
| Parameter | Specification |
|---|---|
| Model | EPN (Electroporation Needle System) |
| Technology | Auto-microneedling + electroporation (dual-action) |
| Device Class | Class II medical device |
| Needle Type | 9-pin, 33G stainless steel, disposable, anti-reflux |
| Needle Depth | 0.0–2.0 mm (infinitely adjustable) |
| Speed | 3 levels (4,000 / 4,500 / 5,000 rpm) |
| Electroporation | 5 adjustable levels |
| Display | LCD (speed, time, energy level) |
| Voltage | AC 100–240 V, 50/60 Hz (DC 12 V, 1 A output) |
| Power Consumption | 50 VA |
| Continuous Operation | 30 minutes |
| Dimensions | 27.85 × 39.5 × 186.5 mm |
| Weight | ~95 g |
| Absorption Boost | Up to 20× vs topical application |
| Certification | CE, ISO 13485, RoHS |
Key Features

Dual-Action: Microneedling + Electroporation
Mechanical collagen induction plus electrical transdermal delivery in a single pass — two therapies, one device.
Up to 20× Serum Absorption
Electroporation opens transient hydrophilic pores, pushing active ingredients far deeper than topical application alone.
Adjustable 0.0–2.0mm Depth
Infinitely adjustable needle depth — fine lines to deep acne scars with precise, indication-specific control.
9-Pin 33G Disposable Cartridges
Medical-grade stainless steel needles with anti-reflux design for hygienic, minimal-trauma single-use treatments.
5-Level Electroporation
Adjustable intensity to match different skin types, indications and client comfort levels.
Class II Medical Device
CE + ISO 13485 + RoHS certified — clinical-grade safety your practitioners and clients can trust.
Treatment Applications

EPN Electroporation Pen vs Conventional Derma Pen
| Dimension | EPN Electroporation Pen | Conventional Derma Pen |
|---|---|---|
| Technology | Microneedling + electroporation | Microneedling only |
| Serum Absorption | Up to 20× deeper | Surface topical only |
| Serum Delivery Depth | Transdermal (dermis) | Surface application |
| Electroporation Levels | 5 adjustable | None |
| Treatment Scope | Rejuvenation + hair + scars | Collagen induction only |
| Needle Cartridge | 9-pin 33G anti-reflux | Standard needle |
| Device Class | Class II medical device | Often unclassified |
| Certification | CE + ISO 13485 | Often uncertified |
What’s in the Box

Return on Investment
| Treatments per Day | 3–5 sessions |
| Revenue per Day | $450 – $1,500 |
| Working Days per Month | 22 days |
| Monthly Revenue Potential | $9,900 – $33,000 |
| Wholesale Machine Cost | $300 – $450 |
Get Wholesale Pricing on the EPN Electroporation Microneedling Pen
Dual-action microneedling + electroporation for 20× serum absorption. 0.0–2.0mm adjustable depth, 9-pin 33G cartridges. Class II medical device, CE + ISO 13485. Clinic & distributor pricing — worldwide shipping available.
Frequently Asked Questions
How does electroporation differ from a standard derma pen?
What conditions does the EPN treat?
How deep do the needles penetrate?
Is the EPN treatment painful?
How many sessions are needed for results?
How does electroporation improve serum absorption?
Is the EPN CE / ISO certified?
Do you offer wholesale / OEM pricing?
Related Products
Professional Microneedling Pen
Explore our full range of adjustable-depth microneedling pens for estheticians and clinics.
M20 Hydra Derma Pen
Add hydra infusion and LED light therapy to your microneedling menu with the M20.
UM8 Hydra Microneedling Pen
A serum-infusion microneedling pen with adjustable speed and depth for facial treatments.
Gold RF Microneedle Machine
Combine mechanical microneedling with fractional RF for deeper skin remodeling.
